The 1st Evidence-Based Research Conference “Increasing the Value of Research” was an online conference held on 16th-17th November 2020. It looked at making research ethical, relevant and worthwhile through the use of systematic reviews to decrease research waste and increase research value. The conference theme reflected the ambition to ensure that all new studies address research questions that matter, in a valid, efficient and accessible manner. One key step towards this goal is to start using prior research in a systematic and transparent way to justify and design new studies. This approach will help ensure that ethical approval, funding and publication is reserved only for necessary studies – those based on knowledge gaps identified through syntheses of earlier trials – and relevant studies – those justified by obtaining the perspective of end-user groups directly affected by the new study. The Conference was aimed not only at researchers from all disciplines but at everyone keen to share their knowledge and experience relevant to an EBR approach.
Chair: Klara Brunnhuber, Vice-chair: Matthew Westmore 0:00:02 Welcome by Maritta Valimaki and Klara Brunnhuber 0:13:10 Hans Lund “The Evidence-Based Research (EBR) concept” 0:40:27 Rieke van der Graaf “The ethical aspect of EBR: the question of valuable research” 1:08:25 Q&A with Hans Lund and Rieke van der Graaf
Plenary 2: Using the Evidence-Based Research approach
Chair: Hans Lund 0:00:44 Michel Shamy “Equipoise and EBR – the need to justify a new RCT” 0:31:08 Alex Sutton “When is a further clinical trial justified?” 1:03:05 Q&A with Michel Shamy and Alex Sutton
Plenary 3: Metaresearch
Chair: Livia Puljak 0:00:45 Introductions 0:02:43 Livia Puljak “What is metaresearch, and how should we call it” 0:12:15 Dawid Pieper “What is a meta-epidemiological study?” 0:28:36 Lawrence Mbuagbaw and Daeria Lawson “The METRIC Project” 0:40:45 Panel discussion
Plenary 4: Current and future challenges for the EBR Approach
Chair: Jennifer Yost 0:00:56 Jeremy Grimshaw “Evidence-Based Research in the Time of COVID” 0:29:14 Q&A with Jeremy Grimshaw 0:42:36 Karen Robinson “Evidence-Based Research – The Future?” 1:02:59 Q&A with Karen Robinson and Jeremy Grimshaw 1:30:33 Close of Conference with Miloslav Klugar, Hans Lund and Maritta Valimaki
Kirsi Hipp: User involvement in research: challenges and opportunities in conducting systematic reviews
Jingjing Meng: Non-pharmacological therapies for improving sleep quality in people living with HIV: Do we still need new studies?
Alejandra Recio-Saucedo: What works in peer review and decision-making approaches to grant funding allocation: a realist synthesis
Jong-Wook Ban: Waste in external validation studies of clinical prediction rule (CPR): Recursive cumulative meta-analyses of Framingham Wilson coronary heart disease rule
Robert Prill: Protocol for a mixed method approach on Scientific Medical Journals’ barriers and facilitators for the reduction of research waste – an EVBRES initiative
Silvia Capikova: How Can Sociological Approach to EBM be Useful for EBR Implementation?
Anna Prokop-Dorner: ‘There is no interest in evidence-based research, actually’ – a qualitative study on barriers and facilitators of implementing EBR approach
Mateusz Swierz : Comparability of quality assessments of systematic reviews/meta-analyses in nutrition using AMSTAR-2 and ROBIS
Julian Hirt : Educational interventions to improve literature searching skills: A scoping review of intervention studies
Hazel Roddam: ReSNetSLT: Using a conceptual value creation framework to evaluate the impact of an online initiative for promoting evidence-based research in allied health
Raluca Sfetcu and Lisa Affengruber: Increasing the value of research by improving the efficient production and updating of systematic reviews
Ci Zhang: Effectiveness and safety of providing free HIV self-testing kits among men who have sex with men in China: is there a knowledge gap?
Käthe Goossen: Strategies for effective study author contact to leverage existing research data when preparing systematic reviews – a randomised study within a review (SWAR)
Cristhian Morales-Plaza: Developing questions for rapid reviews based on the routine use of medical data to identify adverse drug reactions (ADRs)
Katarzyna Klas: Ethics of clinical trials during the SARS-CoV-2 pandemic – preliminary findings of trial informativeness
Matthias Briel: Quality of clinical trial protocols – evidence for improvement? The Adherence to SPIrit Recommendations in Switzerland, Canada, and Germany (ASPIRE-SCAGE) Study
Karolina Strzebonska: Publication and reporting of clinical trial results: cross sectional analysis across academic medical centers
Paulina Glodo: Research waste in published systematic reviews regarding coffee consumption and cancer risk
Deepti Beri: Prevention, management, and control of leptospirosis in India: An evidence gap map
